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Mutagenesis Services

Site-directed mutagenesis is central to molecular biology, facilitating research in a variety of fields, including studies of gene regulatory elements, DNA-protein interaction, protein structure/function, enzyme active sites, and novel proteins. GenScript's site-directed mutagenesis services, powered by sophisticated gene synthesis technology and high performance GS polymerase, include point mutations, deletions, and insertions. They can be customized to fit any scientific applications.


  • Unparalleled Accuracy: GenScript's high performance GS polymerase ensures accuracy of mutants, avoiding creation of unwanted mutations.
  • Unlimited Sites: Using our sophisticated mutagenesis technology, GenScript can introduce mutations at any site.
  • Mutation on Large Construct: Our technology is optimized to introduce mutations, insertions, and deletions on constructs as large as up to 12 kb (including target gene and its vector).
  • Comprehensive Service Package: We offer comprehensive upstream and downstream services, including template sequencing, expression vector construction, and protein expression and purification
  • Most Competitive Prices


Sample Submission Requirements

Please provide following:

  • The complete sequence of the template including the target gene and its vector
  • Mutation specifications
  • Maps and antibiotic resistance of the template and destination vectors
  • Recommended to send 4 μg of template DNA as the starting material. If the starting material is bacterial culture, please send the culture at sufficient amount.


Delivery Specifications

The delivery package includes:

  • 4 μg lyophilized destination vector containing the gene
  • Sequence chromatograms covering your gene (electronic)
  • Construct map for the plasmid (electronic)
  • Quality assurance certificate


For detail information and orders, please contact us at